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Developing a system to simultaneously detect genetic and epigenetic information
Dr Benjamin Schuster-Böckler wins funding to develop algorithms that can identify both genetic variation and DNA methylation from the same sequencing data, with applications in biomedical research and detection of diseases such as cancer.

Early Detection of Cancer Month
A summary of Early Detection Month in Oxford, February 2021

New Oxford spin-out Singula Bio launches
Singula Bio, co-founded by Professors Ahmed Ahmed, Enzo Cerundolo and Enda McVeigh from the Nuffield Department of Women’s & Reproductive Health, aims to become a world leader in developing neoantigen-based individualised cell therapies to use against difficult-to-treat solid malignancies such as ovarian cancer.

New Oxford technology assesses cancer patient vulnerability to COVID-19
New research from Prof Julia Hippisley-Cox has resulted in thousands of cancer patients being given prioritised access to the COVID-19 vaccine.

Finding extracellular vesicle biomarkers for oesophageal cancer early detection
Prof Deborah Goberdhan’s lab is investigating extracellular vesicles and the proteins they express as potential biomarkers for the progression from Barrett’s Oesophagus to oesophageal cancer

Detecting for multiple cancers in one simple test
Prof. Jason Davis is working alongside clinicians to introduce his biomarker assays into the clinic. Using a range of electroanalytical methods, together with electrode arrays and microfluidics, the platform has the potential to test for many types of cancers all at once, and at an earlier, pre-symptomatic stage.

Understanding how inherited and acquired mutations interact to affect cancer
Development fund awardee Gareth Bond is investigating how different types of genetic mutations cooperate to influence cancer risk, progression and response to therapy

Reprogramming tumour cells using an antimalarial drug
Results from the ATOM clinical trial at the University of Oxford have shown that the anti-malarial drug Atovaquone can reduce very low oxygen tumour environments. This has the potential to make cancers behave less aggressively and to improve the impact of everyday cancer treatments.

Studying viral genetics to aid liver cancer early detection
Professor Ellie Barnes and Dr Azim Ansari receive funding to identify cancer-associated strains of hepatitis C in Pakistan to improve assessment of liver cancer risk