CRUK Oxford Centre to Host International Symposium on Oesophageal Cancer

The Cancer Research UK Oxford Centre, Cancer Research UK, Cambridge Cancer Centre and Chinese Hospital Chinese Academy of Medical Science (CICAMS) have come together to host an International Symposium on Oesophageal Cancer.

The symposium is being co-organised by Professor Xin Lu, Professor Rebecca Fitzgerald and Professor Qimin Zhan. Speakers that cover the breadth and depth of Oesophageal Cancer Research will be in Oxford on June 6-7th for this innovative event.

We are pleased to confirm that registration is now open and details can be found here.

Why oesophageal cancer?

Investigating oesophageal cancer presents unique opportunities for advances on two fronts: addressing the substantial unmet clinical needs of this disease; and uncovering molecular mechanisms with broad implications for our understanding of tumorigenesis.

The oesophagus provides an unusual yet accessible tumour context. In the lower oesophagus, the squamous epithelium of the oesophagus meets the columnar epithelium of the stomach and oesophageal adenocarcinoma is often preceded by epithelial cellular changes in an inflammatory condition called Barrett’s oesophagus. This setting thus presents a unique model for studies of the fundamental principles of interactions among different epithelial cell types, how signalling and differentiation are disrupted in cancer development and the influence of immune responses and inflammation on cell fate. On a global scale oesophageal squamous cell cancer is a major cause of cancer related death with some very high incidence areas thus providing further opportunities for investigating the epidemiology and causation of this disease and potential avenues for treatment.

Oesophageal cancer research is thus an ideal forum to bring together cell biologists, geneticists, immunologists and clinicians.