Cancer Research UK Oxford Centre Announces Prof. Xin Lu as New Co-Director

The Centre is pleased to announce the appointment of Professor Xin Lu as Co-Director of the Centre, leading on the development of our scientific strategy. Professor Lu is an internationally recognised cancer biologist who combines ground-breaking laboratory research with experimental medicine. She has made major advances in understanding regulation of the tumour suppressor p53, revealing new ways selectively to kill cancer cells. Professor Lu is Director of the Oxford Branch of the Ludwig Institute for Cancer Research.

Professor Mark Middleton, Co-Director of the Centre, said: “I am delighted that Xin has agreed to join me in leading the Cancer Research UK Oxford Centre. Her expertise will be invaluable in developing the Centre’s strategy and in increasing engagement with fundamental science groups across Oxford. Her involvement in the NIHR Biomedical Research Centre and with the international Ludwig community will be great assets in our drive to make the most of Cancer Research UK’s investment here.”

David Scott, Director of Discovery Research and Research Communications at Cancer Research UK said: “Professor Lu’s appointment is fantastic news for the CRUK Oxford Centre; her skills and experience in leading the Ludwig Institute for Cancer Research Oxford will be invaluable to foster further collaboration and accelerate progress in translating cancer research for patient benefit.”

Simon Leedham awarded the Cancer Research UK Future Leaders in Cancer Research Prize

Today at the NCRI Annual Conference Professor Simon Leedham was awarded the Cancer Research UK Future Leaders in Cancer Research Prize.

Simon is a Cancer Research UK Clinician Scientist Fellow at the Wellcome Trust Centre for Human Genetics. His research has made important advances in the cell biology and molecular pathogenesis of gastrointestinal cancers and advanced our understanding of the role of BMP signalling in colorectal tumorigenesis.
In awarding the Future Leaders Prize to Simon, the selection panel from CRUK recognised his role in understanding the importance of the BMP antagonist, GREM-1, in colorectal neoplasia. This revealed a mechanism of hereditary polyposis and its importance in spontaneous colorectal cancer. Simon’s work has shown that cross-talk between conserved BMP signalling and notch, in a subtype of colorectal cancer, promotes poor prognosis. His more recent work is leading him into novel approaches to therapy.

The Panel regarded Simon to be a leader based on the quality of his research and his collaborative efforts, demonstrated by the number of prestigious conferences he has spoken at. The Panel considered Simon’s work to be widely recognised internationally, and that he is an excellent clinician-scientist, with strong leadership skills.

Awarding the Prize at the NCRI Conference, Sir Harpal Kumar noted the Panels confidence that Simon will continue to make significant contributions to the field and that these will drive cancer research forward.