Entries by Oxford Centre

New dual-action cancer-killing virus

Scientists have equipped a virus that kills carcinoma cells with a protein so it can also target and kill adjacent cells that are tricked into shielding the cancer from the immune system. It is the first time that cancer-associated fibroblasts within solid tumours – healthy cells that are tricked into protecting the cancer from the […]

Transatlantic collaboration to support earlier detection of pancreatic and oesophageal cancer

Oxford researcher Chunxiao Song, who is a group leader and chemist at the Ludwig Institute for Cancer Research, recently gave an interview to CRUK speaking about his work recently funded by the CRUK-OHSU Project Award. The Award is jointly funded by CRUK and Oregon Health and Science University (OHSU). In collaboration with Dr Thuy Ngo […]

Marseille-Oxford Cancer Centres Collaboration (MOC3)

  October 4th and 5th 2018 saw the first Marseille-Oxford Cancer Centres Collaboration  (MOC3) meeting, held in the beautiful location of Villa Gaby, Marseille. The meeting was held to initiate a new partnership between the Cancer Research UK Oxford Centre, the Cancer Research Centre of Marseille and the Institut Paoli-Calmettes. The objectives of these cancer […]

Metabolic profiles of breast cancer linked to response to metformin treatment

  (B)(extract): Static PET-CT images in coronal plane pre- and post-metformin are from an individual with an increase in KFDG-2cpt following metformin;note increased uptake in axillary lymph nodes (circled).     An international collaborative team of medical oncologists, radiologists, cell biologists and bioinformaticians led from Oxford by Simon Lord and Adrian Harris, have identified different […]

AstraZeneca – Oxford Cancer Symposium (AZOCS), Thursday 13th September 2018 | Keble College, Oxford

  AstraZeneca – Oxford Cancer Symposium (AZOCS) Thursday 13th September 2018 | Keble College, Oxford   On Thursday 13th June, Keble College in Oxford hosted the inaugural AstraZeneca – Oxford Cancer Symposium (AZOCS).   Over 125 researchers from Oxford and 90 cancer scientists from AstraZeneca and MedImmune attended to develop and establish a series of […]

Pioneering Combination Therapy Approach to Treating Colorectal Cancer

Celleron Therapeutics, the UK-based company and Oxford University spin-out developing personalised medicine for cancer patients, has today announced the initiation and first patient enrolment of its clinical study that will evaluate the effect of a novel combination therapy approach for colorectal cancer. Professor Mark Middleton, Consultant Medical Oncologist and Professor of Experimental Cancer Medicine at […]

Rare cancer could be caught early using simple blood tests

A pioneering study into myeloma, a rare cancer, could lead to GPs using simple blood tests to improve early diagnosis. CRUK Centre members, in collaboration with the University of Exeter and Chiddenbrook Surgery, Crediton, found that a simple combination of blood tests, which are routinely conduced in GP surgeries, could improve early diagnosis of myeloma. […]

Oxford researchers discover DNA repair protein complex important in drug resistance in cancers driven by BRCA mutations.

A team of Cancer Centre researchers lead by Associate Professor Ross Chapman have discovered a novel DNA repair protein complex called ‘Shieldin’. Published in Nature, the paper describes the identification of ‘Shieldin’, which was shown to be essential for generating genetic diversity in antibodies produced during immune responses. When activated following an infection or immunisation, B […]