Annual Symposium

The Centre’s Annual Symposium is the physical manifestation of the wealth of excellence we have here in Oxford and the passion and commitment to cancer research that is shared across our community. The programmes showcase the breadth of activity across the Centre and often feature cross-departmental or interdisciplinary partnerships supporting translational cancer research in Oxford.

The Symposium provides an opportunity for our members to network and often sparks new opportunities for partnership. It is also provides a platform to highlight our younger scientists through poster competitions and presentations from Centre-funded students.

2018 Symposium

On Friday 15th June, Oxford University’s Mathematical Institute hosted the 7th Annual CRUK Oxford Centre Symposium showcasing world leading early detection, haematological and microenvironment cancer research.

The centre was pleased to welcome Professor Ketan Patel who gave his keynote lecture on the metabolic origins of endogenous DNA damage in blood stem cells. We are also very grateful to our guest speaker Susan Cakebread who talked about her story from cancer diagnosis, treatment, disease relapse, clinical trial participation and eventual response.

We’d like to thank all those who attended, submitted abstracts and presented their posters all of whom contributed to an exciting and enjoyable event. Special mention should be made of this years poster prize winners and to those who were selected to give prize talks.

The prize talks were awarded to:
Mr Phillip Kruger (DPhil Prize talk), Sir William Dunn School of Pathology. Receptor Downregulation Leads to Desensitisation of CAR T Cells and is Overcome by Costimulation
Dr Bilyana Stoilova (Post Doc Prize talk), Radcliffe Department of Medicine. Single-cell analysis reveals the continuum of human lympho-myeloid progenitor cells
Dr Victoria Woodcock (CRTF Prize talk). Characterising the antigen specific T cell response to immunotherapy treatment in cancer

The posters selected for the CRUK Oxford Centre 2018 Poster Prizes were:
Miss Zhiyuan Hu, WTCHG. Towards understanding initiation of ovarian cancer by single-cell RNA sequencing
Dr Samantha Hopkins, Oxford Institute for Radiation Oncology. Non-invasive in vivo imaging of p53 in mouse models of Pancreatic Ductal Adenocarcinoma
Mr Liam Brown, Mathematical Institute. Quantifying physiological limits for rates of immune cell entry into tumours and tissues

If you attended the Symposium and would like to find out any more information about any of the presentations you saw, any of the posters, or further information on the CRUK Oxford Centre then please contact cancercentre@oncology.ox.ac.uk

2017 Symposium

The 2017 Cancer Research UK Oxford Centre Symposium was held on Friday 23rd June at the Saïd Business School.  

2015 Symposium – 5th June, Mathematical Institute

Thank you to all the CRUK Oxford Centre members that attended the Symposium on Friday 5th June.

We were delighted to welcome back a CRUK Oxford Centre funded DPhil student, Johanna Rankin (Prof Sarah Darby, Clinical Trials Service Unit), and Clinical Research Training Fellow, Kezia Gaitskell (Prof V. Beral & Prof A. Ahmed, Cancer Epidemiology Unit / Nuffield Department of Obstetrics & Gynaecology), to give prize talks. The Centre is proud of the achievements of these students and we were thrilled to welcome some of the brightest and best at the symposium this year. The post-doc prize talk was given by David Clynes (Prof R. Gibbons & Prof D. Higgs Lab, Weatherall Institute of Molecular Medicine), who was chosen to present his work on supression of the alternative lengthening of telomere pathway by the chromatin remodeling factor ATRX.

A number of collaborative showcases illustrated the successes that come from interdisciplinary work, and we also welcomed some new Centre members to the stage to share the skills they have bought to Oxford. The Centre was thrilled to have Professor Sir David Lane at the Symposium to deliver the keynote lecture. David described the generation and identification of point mutation specific antibodies as well as antibodies that mimic the T cell receptor by recognizing the neoantigen peptide MHC complex as the concept of cryptic epitopes . He also reviewed the recent data that suggests that intracellular antigens may also be viable targets for immune therapy approaches.

We’d like to thank all those who submitted abstracts and presented their posters at the Symposium. It was a brilliant opportunity for all attendees to find out about the world-leading science taking place here in Oxford. Congratulations to the Centre members who were awarded the poster prizes by the judging panel. The judges were especially impressed by the scientific content of the posters, the knowledge of the presenters, and the way the data had been displayed.

The posters selected for the CRUK Oxford Centre 2015 Poster Prizes are:

  • Polymorphisms in the P53 pathway are enriched in Cancer Susceptibility Loci and share Charactertistics with Somatic Pathway MutationsGiovanni Stracquadanio, Bond Lab, Ludwig Institute for Cancer Research
  • Dose-escalated radiotherapy for NSCLC: heart dose versus survival in IDEAL-CRTSindu Vivekanandan, Hawkins / Fenwick Lab, CRUK / MRC Oxford Institute for Radiation Oncology
  • The role of exosome signalling in the development and progression of prostate cancerKristie McCormick, Goberdhan Lab, Department of Physiology, Anatomy and Genetics

If you attended the Symposium and would like to find out any more information about any of the presentations you saw, any of the posters, or further information on the CRUK Oxford Centre then please contact cancercentre@oncology.ox.ac.uk