Today at the NCRI Annual Conference Professor Simon Leedham was awarded the Cancer Research UK Future Leaders in Cancer Research Prize.
Simon is a Cancer Research UK Clinician Scientist Fellow at the Wellcome Trust Centre for Human Genetics. His research has made important advances in the cell biology and molecular pathogenesis of gastrointestinal cancers and advanced our understanding of the role of BMP signalling in colorectal tumorigenesis.
In awarding the Future Leaders Prize to Simon, the selection panel from CRUK recognised his role in understanding the importance of the BMP antagonist, GREM-1, in colorectal neoplasia. This revealed a mechanism of hereditary polyposis and its importance in spontaneous colorectal cancer. Simon’s work has shown that cross-talk between conserved BMP signalling and notch, in a subtype of colorectal cancer, promotes poor prognosis. His more recent work is leading him into novel approaches to therapy.
The Panel regarded Simon to be a leader based on the quality of his research and his collaborative efforts, demonstrated by the number of prestigious conferences he has spoken at. The Panel considered Simon’s work to be widely recognised internationally, and that he is an excellent clinician-scientist, with strong leadership skills.
Awarding the Prize at the NCRI Conference, Sir Harpal Kumar noted the Panels confidence that Simon will continue to make significant contributions to the field and that these will drive cancer research forward.